New treatments for hyperkalaemia: clinical use in cardiology

Clinical Cardiology: New Frontiers Thrombolysis for Acute Myocardial Infarction

Thrombolytic therapy has been a major advance in the management of acute myocardial infarction. Unfortunately, it continues to be underused or is administered later than is optimal. Thrombolytic therapy works by lysing infarct artery thrombi and achieving reperfusion, thereby reducing infarct size, preserving left ventricular function, and improving survival. The most effective thrombolytic reg...

New Methods for Eliminating Inferior Treatments in Clinical Trials

To my parents, my brother, and Wei-yu. iii ACKNOWLEDGEMENTS I would like to thank a number of individuals for their support and assistance during my study at Georgia Tech. Foremost, I want to express my special gratitude to my advisor, Dr. Anthony Hayter, for his inspiration, guidance, and encouragement. He helps me a lot through the whole Ph.D. study. I am grateful to Dr. Alexander Shapiro for...

The use of the phonocardiograph in clinical cardiology.

The phonocardiograph was born soon after the electrocardiograph, but their growth has been unequal in that the latter has been applied immediately to clinical medicine and has flourished while the former test, used to display such murmurs as the presystolic and the one identified with patent ductus arteriosus, has become largely exhibitional and for that reason has lost ground. More recently, h...

new clinical implications of opiate maintenance treatments

Hyperkalaemia.

Hyperkalaemia is defined as serum potassium concentration greater than 5.5 mmol/l. Its prevalence in the general population is unknown, but it is thought to occur in 1-10% of patients admitted to hospital.1 The rate of morbidity and mortality associated with hyperkalaemia has risen greatly with the use of drugs that target the renin-angiotensin system, and since publication 10 years ago of a ra...